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diagnosis differential hematology management secondary algorithm common cryofibrinogenemia cvid endocarditis extravascular hemeonc hemolytic hemophagocytic hlh hypogammaglobulinemia immunodeficiency immunology infectiousdiseases intravascular
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): ... ) - HELLP syndrome ... uremic syndrome ... #anemia
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
halt nail growth (e.g ... lines, usually painful ... • Nephrotic syndrome ... #Secondary #dermatology ... Diagnosis #Algorithm #causes
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... malignancies • Anemia ... iron deficiency, hemolysis ... Myelodysplastic syndrome ... #hematology #secondary
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
neuropathy) • Systemic ... • Coombs (-) hemolytic ... anemia due to cold ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
associated with systemic ... onset of tender or painful ... Causes: - Idiopathic ... #diagnosis #dermatology ... #oncology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
and autoimmune hemolytic ... anemia) • Systemic ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
Palpitations - Differential Diagnosis Framework What? • It is an unpleasant awareness or sensation that the heart is
exam • 12-lead ECG ... Valvular disease (e.g ... Anticholinergics Systemic ... Hyperthyroidism • Anemia ... #Palpitations #Cardiology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulin (CG ... processes: • Systemic ... sensitivity • Painful ... cryoglobulins • Negative causes ... Antiphospholipid syndrome
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Vascular: • Systemic ... Cholesterol emboli syndrome ... Septic emboli cause ... Leukocytosis, anemia ... Differential #Diagnosis #cardiology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome ... caused by uncontrolled ... of the immune system ... - Cytopenias (anemia ... Diagnosis #Management #Hematology
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