7 results
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
: • Severe adverse ... • Facial Edema ... Resolution > 15 days Differentials ... #Syndrome #dermatology ... #diagnosis #management
Restrictive Cardiomyopathy - Diagnosis and Causes
Clinical: Dyspnea, Exercise Intolerance, ↑ "Right Sided-Symptoms" (ascites, hepatomegaly, ↑↑peripheral edema)
Physical
↑ "Right Sided-Symptoms ... , ↑↑peripheral edema ... i.e., Radiation, Chemotherapy ... #Causes #differential ... #cardiology #algorithm
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... - Cytotoxic chemotherapy ... Syndrome #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... myalgias, HoTN, edema ... : >3 symptoms, or ... initiation • Differential ... #management #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
disease, Cancer chemotherapy ... Etiology: • Pathophysiology ... Neurological symptoms ... Reversible course Differential ... #management #neurology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
and Peripheral Edema ... the determined cause ... #diagnosis #differential ... #algorithm #management ... icu #clinical #pharmacology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Causes progressive ... fasciculations Common Symptoms ... conditions listed in differential ... #management