11 results
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Basophilia - Differential ... Diagnosis Framework Basophils ... blood cell count Basophils ... Hypersensitivity Or Inflammatory ... Influenza • Chickenpox
Anaphylaxis: Pathogenesis
Anaphylaxis is a Type 1 hypersensitivity reaction
While the primary mechanism of anaphylaxis is mast cell
cell activation, basophils ... production of inflammatory ... Recruitment of inflammatory ... pathophysiology #immunology
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Inflammatory mechanism ... mast cells, and basophils ... mast cells and basophils ... the release of inflammatory ... #immunology
Inflammatory, Immunologic, and Pathobiologic Features Leading to Severe Asthma. #Pathophysiology #Asthma #Mechanism #Leukotriene #Type2 #Inflammatory #Immunologic
Inflammatory, Immunologic ... Leukotriene #Type2 #Inflammatory ... #Immunologic #NEJM
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Inflammatory Cascade ... cell activity #Inflammatory ... pathophysiology #immunology
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
crusts/erosions - Inflammatory ... Varicella zoster (chickenpox ... intact blisters - Inflammatory
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
the epidermis 2) Inflammatory ... Eosinophils 3) Basophils
Allergic Rhinitis: Pathogenesis and clinical findings

1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
nasal mucosa and basophils ... mast cells and basophils ... > Mast cells & basophils ... Recruitment of inflammatory
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
release the pro-inflammatory ... secretion • Inflammatory ... HypersensitivityReaction #Allergy #Immunology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Gastrointestinal inflammatory ... hypogammaglobulinemia #immunology