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diagnosis cppd management disease pseudogout signs chondrocalcinosis hematology alkaline alp approach arthritis comparison deposition differential gout hemeonc hemophagocytic hepatology hlh
Pseudogout: pathogenesis and clinical findings - Idiopathic (vast majority of cases) -> Mechanism unknown - Familial
> Clearance of calcium ... mineralization of calcium ... joint (sudden onset ... Disease #Signs #Symptoms ... #Pathophysiology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... changes, stroke symptoms ... Lysis Syndrome: • Pathophysiology ... diagnosis #management #hematology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
or nerve root Symptoms ... pyrophosphate dihydrate ... • Basic calcium ... hydroxyapatite) • Calcium ... Joint #Pain #MSK #rheumatology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
• Inorganic pyrophosphate ... collection with EDTA Pathophysiology ... ALP -> PPi and Calcium ... PPi (inorganic pyrophosphate ... mineralization Symptoms
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pyrophosphate Deposition ... Disease (CPPD) Pathophysiology ... : Pyrophosphate ... characterized by sudden onset ... Deposition #Disease #Rheumatology
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... : • Pyrophosphate ... precipitates with calcium ... • Nocturnal onset ... Gout #Comparison #rheumatology
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease - Acute CPPD precipitation into the joint space ->
Chondrocalcinosis: Calcium ... Pyrophosphate Dihydrate ... Disease #Signs #Symptoms ... #Pathophysiology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
4) Average age onset ... survival is 93-95% Pathophysiology ... fibrosis. 4) Calcium ... Features: • Many symptoms ... patients have no symptoms
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
- Onset: Usually ... Common Signs and Symptoms ... Pathophysiology ... Diagnosis #Management #Hematology
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