12 results
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
(PSC) PSC is a ... extra-hepatic bile ducts, commonly ... • COLITIS - PSC-IBD ... judicious use of ERCP ... with UDCA remains common
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Intestine - Other causes ... Malignancy Most common ... Primary biliary Cholangitis ... (PBC) - Other ... Infiltrative diseases - PSC
Proposed Schema for the Management of Pruritus in Primary Biliary Cholangitis (PBC). 

Cholestyramine up to 4g
(PBC). ... Recirculating System; CBD ... , common bile duct ... #PBC #Management ... #Hepatology #Algorithm
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Diagnosis Algorithm ... • Drugs • AIH ... Bile Ducts • PSC ... Bile Ducts • Common ... #Causes
Unintentional Weight Loss in Primary Care
 • Definition: More than 5% reduction in body weight within
-12 months, Is associated ... Baseline evaluation: CBC ... LDH, UA Most Common ... Causes: - Malignancy ... PrimaryCare #diagnosis #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... tract, and often causes ... (Commonly MPO-ANCA ... : (± 100 % Commonly ... Lab Tests: • CBC
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... Diagnosis The most common ... > 4 mmol/L was associated ... www.ncbi.nlm.nih.gov/pmc ... Acidosis #Elevation #Differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Antiribosomal P, APLA, PAC ... titers > 1:80 • CBC ... Kidney disease common
Fever After International Travel

Infectious Disease:
• Endemic in either the destination or home region

Viral Syndromes:
Arboviral infections, a
infections, a common ... cause of febrile ... illnesses associated ... Investigations: • CBC ... Fever #Travel #Differential
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... Diagnosis: On the CBC ... thrombocytosis, only other commonly ... ET-associated mutation ... • Treatment algorithms