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diagnosis hepatology primary gastroenterology management sclerosing abdominal alkaline autoimmune biliary cancer cirrhosis elevation fat hematology hepatitis injury liver malabsorption myopathy
Primary sclerosing cholangitis (PSC) - Malignancy Screening and Surveillance Recommendations Cholangiocarcinoma - Annual US or
(PSC) - Malignancy ... - Annual US or MRCP ... q 6 months +/- AFP ... CRC - IBD - ... #PSC #Malignancy
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Intestine - Other causes ... Leukocytes • Malignancy ... Primary biliary Cholangitis ... (PBC) - Other ... Infiltrative diseases - PSC
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Diagnosis Algorithm ... Vascular Causes ... Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... , PBC, PSC, Cystic
Causes of Fat Malabsorption - Differential Diagnosis Biliary Duct Obstruction • Autoimmune— PBC, PSC • Infection— liver
Causes of Fat Malabsorption ... - Differential ... • Autoimmune— PBC ... , PSC • Infection ... - Acquired • Chronic
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
(PSC) PSC is a ... chronic, cholestatic ... • COVERT - PSC ... • COLITIS - PSC-IBD ... judicious use of ERCP
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential ... Diagnosis Algorithm ... Artifact (redo CBC ... : • Acute or Chronic
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
) - Summary PBC ... intralobular bile ducts causes ... obstruction • ALP ... bile ducts Differential ... - gallstone or malignancy
Chronic Abdominal Pain Causes - Differential Diagnosis Framework Many patients with chronic abdominal pain have had prior
Pain Causes - Differential ... dysfunction • PSC ... PUD • Gastric malignancy ... • Esophageal malignancy ... #Causes #Differential
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... lung disease Malignancy ... Polymyositis or ALS ... statins - probably caused ... Other Diseases: • PBC
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