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diagnosis hematology differential management oncology workup blood cancer causes chronic classification cobalamin deficiency essential lymphocytic lymphomas lymphoproliferative markers mds mentzerindex
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Acute • Myloid (AML ... Pseudo Pelger-Huet, Macrocytic ... anemia - ... • Lymphoid (CLL ... Thrombocytosis (ET
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Algorithm Mean ... (EPO), iron or B12 ... (BM) ablative disorders ... #Workup #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
malignancies • Anemia ... Chronic inflammatory disorders ... thrombocythemia (ET ... Chronic myeloid leukemia ... (CML) - Dr.
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
lymphoproliferative disorders ... • Neutropenia, anemia ... microglobulin Treatment ... Transform to DLBCL, PML ... leukemia #CLL
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... MCV 80-100 fl) & macrocytic ... a decrease in all ... hemoglobin of less than 12 ... that involves disorders
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... involve one, two, or all ... common cytopenia: Macrocytic ... (CML) • Felty ... Nutritional: vitamin B12
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
dysfunction, and/or disorders ... : • Worsening macrocytic ... level (< 200 pg/mL ... Check for IF ab Treatment ... diagnosis e.g. leukemia
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... Differential Diagnosis Algorithm ... Responsive to Treatment ... Treated Like Acute Leukemias ... relapse - Amy
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
generally requires all ... hemoproliferative disorder ... PV, MDS, CML) Treatment ... transformation into MDS or AML ... • Treatment algorithms
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
algorithm 2018. ... acute myeloid leukemia ... (AML). ... disease tolerate anemia ... #algorithm #hematology
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