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diagnosis differential hematology algorithm oncology management clinical chronic dermatology lymphadenopathy mnemonic ophthalmology pathology pathophysiology smear cardiology effusion fever generalized neutrophils
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... , CLL Acute leukemias ... Chronic leukemia ... Lymphoblastic Leukemia ... -> AML: Blast crises
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... • Most common leukemia ... - Leukemia cutis ... Confirm: Flow cytometry ... to DLBCL, PML leukemia
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Neoplastic: - Leukemia ... Lymphoblastic Leukemia ... Chronic Lymphocytic Leukemia ... Diagnosis #Algorithm #Causes
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm Infection • Bacterial • Abscess • Viral Medications
Causes of Neutrophilia ... Chronic myelogenous leukemia ... Polycythemia vera Acute Leukemia ... Diagnosis #Algorithm #Causes
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... • Neoplastic (Leukemia ... Diagnosis #Algorithm #Causes
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic Leukemia ... • Most common leukemia ... Peripheral flow cytometry ... #Lymphocytic #Leukemia
Evaluation of Leukocytosis: The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages. Include
Leukemoid reaction ... Leukemias or myeloproliferative ... Leukemoid Reaction ... D/D leukemia: increases ... the underlying cause
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Chronic myeloid leukemia ... Acute myeloid leukemia ... Acute basophilic leukemia ... Chickenpox Other Causes ... Differential #Diagnosis #causes
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... features in most cases ... promyelocytic #leukemia
Hyperviscosity Syndrome - Causes and Treatment - Waldenstrom macroglobulinemia (most common) / Plasmapheresis - Multiple
Hyperviscosity Syndrome - Causes ... Plasmapheresis - Leukemia ... Hydroxyurea - Leukemia ... Hyperviscosity #Syndrome #Causes
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