12 results
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
with devastating differential ... presents in thrombocytopenic ... rash, the diagnosis ... #Diagnosis #Dermatology ... #Purpuric #Rash
Approach to the Rash in a an oncology patient - MINT-C Mnemonic
M - Malignancy: Leukemia cutis,
Coagulopathy: Purpura ... fulminans/DIC, Thrombocytopenia ... #oncology #differential ... #diagnosis #cancer ... MINTC #Mnemonic #dermatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... #Differential # ... Diagnosis #hematology ... #nonpalpable #dermatology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
of Bleeding / Bruising ... - Differential ... Diagnosis Algorithm ... Thrombocytopenia ... #Causes #Hematology
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
or Easy Bruising ... bypass Vascular disorders ... #Bruising #Causes ... #peds #pediatrics ... #diagnosis #differential
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... and Aggregometry ... Gplb receptor • Thrombcytopenia ... #hematology #hemepath ... diagnosis #Aggregometry
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Petechiae/Purpura ... - Diagnostic Algorithm ... vasculitis) or disorders ... #Dermatology #Rash ... Palpable #Algorithm #Differential
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential ... Diagnosis Algorithm ... hemostasis: - Thrombocytopenia ... Vasculitis - Collagen disorders ... #Causes #dermatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
microangiopathy: Thrombotic thrombocytopenic ... purpura (TTP), ... lymphoproliferative disorders ... Extravascular #Causes #differential ... #diagnosis #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
manifestations: from easy bruising ... rash) • Heart, ... leukopenia, anemia, and thrombocytopenia ... Activation #Syndrome #Diagnosis ... #Management #Hematology