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diagnosis hepatology causes algorithm management rheumatology transaminitis ascites injury acute antibodies chronic gastroenterology hepatopulmonary patterns saag secondary abnormal aclf aflp
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Differential Diagnosis ... • NAFLD • Cirrhosis ... #Differential # ... Diagnosis #hepatology
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Inflammation - Hepatitis ... Nonalcoholic fatty liver ... (Budd-Chiari syndrome ... #Diagnosis #Differential ... #Hepatology #Cirrhosis
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 Ascites - Differential Diagnosis Chronic liver disease (cirrhosis or chronic hepatitis) - 80% Underlying malignancy - 10% Congestive heart
Diagnosis Chronic liver ... disease (cirrhosis ... or chronic hepatitis ... Fitz-Hugh-Curtis syndrome ... #Diagnosis #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... CMV), Alcoholic cirrhosis ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Hepatomegaly - Differential ... Non-Malignant • Fatty Liver ... Hemochromatosis • Wilson's Disease ... • Budd-Chiari Syndrome ... Primary Biliary Cirrhosis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
those with CLD (± cirrhosis ... months without treatment ... disease, liver ... #Failure #Cirrhosis ... #Hepatology #gastroenterology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Cholestatic disease ... • Alcoholic hepatitis ... Infiltrative • Cirrhosis ... • Others #LFTs
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... HELLP, Celiac disease ... #Diagnosis #hepatology ... Transaminitis #LFTs ... #hepatitis
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... and hepatorenal syndrome ... • Budd Chiari syndrome ... /acute hepatitis ... sarcoidosis) • Liver
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... obstruction, HELLP Syndrome ... , Celiac Disease ... #Injury #Differential ... Acute #algorithm #hepatology
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