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hepatology algorithm acute aflp biliary chemistry cholangitis coagulation dic disseminated fatty gap globulin hepatomegaly hepatopulmonary hiv hps hypertension interpretation intravascular
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
thrombocytopenia, hepatic encephalopathy ... Clues to non-cirrhotic ... /acute hepatitis ... pregnancy • Primary ... #Diagnosis #causes
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
congenital - Primary ... (Budd-Chiari syndrome ... #Differential # ... Hepatology #Cirrhosis ... #Causes
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 Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Non-Malignant • Fatty Liver ... Hemochromatosis • Wilson's Disease ... • Budd-Chiari Syndrome ... Biliary Cirrhosis ... #Causes #Hepatology
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Causes of Ascites ... Liver disease ... - Cirrhosis ... - Alcoholic hepatitis ... #Causes #diagnosis
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
Causes of Ascites ... - Hepatic: • Cirrhosis ... • Infiltrative disease ... • Acute liver ... #Hepatology #causes
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
develops (DIC, ascites ... hypoglycemia, encephalopathy ... infiltration) Differential ... Hepatitis, Preeclampsia ... #management #pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... /Liver failure ... bile ducts Differential ... Viral hepatitis,
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
INR > 1.5 • Encephalopathy ... : < 1 • Cirrhosis ... • Gilbert's syndrome ... #chemistry #diagnosis ... #differential #
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
vasculitis: 10%-16% Liver ... • Autoimmune hepatitis ... cirrhosis: 3%-20% ... Adenocarcinoma Treatment ... Diagnosis #Management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
DIC • Severe Liver ... Disease: - Impaired ... : • Treat primary ... #causes #treatment ... #management #hematology
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