619 results
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
Pathogenesis and Joint ... poly-articular joint ... Joint involvement ... -> Anti-Cyclic Citrullinated ... space decr joint
Rheumatoid Arthritis
Rheumatoid Arthritis (RA) is an inflammatory autoimmune condition. While chiefly thought of as a joint
thought of as a joint ... the MCP & PIP joints ... affects the DIP joints ... #inflammation #joint ... RANKL #ostoblast #Citrullinated
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
involving small joints ... inflammatory) • joint ... • synovitis; joint ... tenderness • joint ... anti-CCP (cyclic citrullinated
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
spondylitis - Sacroiliac joint ... of the affected joint ... RF) and cyclic citrullinated ... • Sacroiliac joint
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint ... 3) Number of Joints ... weight-bearing joints ... Number of Joints ... late prosthetic joint
Rheumatoid Arthritis - 2020 ACR-EULAR Classification
≥ 6 of 10 points = definite RA
Joint Involvement:
= definite RA Joint ... 2-10 large joints ... , +/- large joints ... points >10 joints ... least 1 small joint
Phalanges - Hand Anatomy

Joints between phalanges are named interphalangeal meaning “between phalanges.” Because each finger has
Hand Anatomy Joints ... interphalangeal joints ... interphalangeal) joint ... interphalangeal) joint
Common Forms of Arthritis in the Hands

Acute Rheumatoid Arthritis 
Tender, painful, stiff joints in rheumatoid arthritis,
painful, stiff joints ... interphalangeal joints ... interphalangeal joints ... (Degenerative Joint ... Joint involvement
Reactive Arthritis
 • Inflammation of joints (commonly large joints)
    - Asymmetric Oligoarthritis: Joint
Inflammation of joints ... commonly large joints ... Oligoarthritis: Joint ... pain in a few joints ... ) - Large Joint
Rheumatoid arthritis (RA): X-ray features
 • Soft tissue swelling (best seen by comparing left & right
together) • Joint ... closer to the joints ... ) • Joint Subluxations ... (Joint deformities