29 results
Hemolytic anemia in Wilson's disease

#Wilsons #Disease #hemolytic #anemia #Hematology #pathophysiology
Hemolytic anemia ... in Wilson's disease ... #Wilsons #Disease ... #hemolytic #anemia ... #Hematology #pathophysiology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... cold agglutin disease ... lymphoproliferative disorders ... differential #diagnosis #hematology ... #anemia
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Differential Diagnosis Algorithm ... • Bleeding • Hemolysis ... #MCV #Classification ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... Consider RBC membrane disorder ... #Anemia #Differential ... #workup #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Microangiopathic Hemolytic ... Unstable hemoglobin disorders ... spherocytosis, Autoimmune hemolytic ... Cold autoimmune hemolytic ... differential #diagnosis #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... Disease • Marrow ... • RBC Membrane Disorder ... #Classification ... #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach ... -100): • Non-hemolytic ... , CKD • Hemolytic ... Non-megaloblastic: Liver disease ... #MCV #Algorithm
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Diagnostic Algorithm ... chronic kidney disease ... Probable bone marrow disorder ... Underproduction #Algorithm ... #hematology #diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... • Symptoms of anemia ... anemia • Cold ... #hemolytic #anemia ... #hematology #diagnosis
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... Schistosomiasis - Chronic hemolytic ... anemia - Persistent ... , thyroid disorders ... Hypertension #PHTN #Classification