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diagnosis differential nephrology management nephritis causes rheumatology treatment alopecia comparison dermatology disorders focal glomerular glomerulonephritis hairloss hematology high hyperkalemia lymphomas
Lupus Nephritis Primer Class I - Minimal Mesangial Class II - Mesangial Proliferative Class Ill - Focal Proliferative Class IV
Lupus Nephritis ... Primer Class I - ... Proliferative Class ... IV - Diffuse Proliferative ... Nephritis #SLE #Classification
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
: • Class I - ... mesangial LN • Class ... proliferative LN • Class ... chronic lesions • Class ... Membranous LN • Class
Algorithm for the Treatment of Membranous Lupus Nephritis Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the ... of Membranous Lupus ... immunosuppression to treat class ... for worsening disease ... therapy to treat class
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Differential Diagnosis Algorithm ... Irreversible-biopsy required • Lupus ... Secondary to Skin Disease ... • Discoid lupus ... #causes
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
selected glomerular diseases ... /nephritis • Lupus ... ISN/RPS class IV ... (diffuse proliferative ... Minimal change disease
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Post-strep GN, Lupus ... involvement: Anti-GBM Disease ... differential #diagnosis #algorithm
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... are present • Classic ... lymphadenopathy more diffuse ... Lymphoproliferative #Disorders #Classification ... #pathophysiology
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Causes of Hyperkalemia ... neuromuscular injury, disuse ... : syßtemic lupus ... High #Potassium #Classification ... #Causes
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