5 results
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
: CLASS 1 - Sodium ... duration: - CLASS ... duration - CLASS ... & AP duration CLASS ... #Classes #pathophysiology
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
Polyarteritis Nodosa (PAN ... Viral replication causes ... direct injury to ... Heart failure - Diffuse ... PolyarteritisNodosa #Pathophysiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
: CLASS 1 - Sodium ... duration - CLASS ... duration - CLASS ... & AP duration CLASS ... #Classes #pathophysiology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
are present • Classic ... lymphadenopathy more diffuse ... , can have extra ... Lymphoproliferative #Disorders #Classification ... #pathophysiology
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
mechanisms: • Direct ... lung injury • Indirect ... pulmonary nodules and masses ... • Patchy or diffuse ... Exclude other causes