15 results
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Primary Routes of Clearance ... , 0% Renal Apixaban ... , 50% Renal Rivaroxaban ... 35% Renal #DOAC ... #Pharmacology #Clearance
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... : Apixaban (25% ... renal clearance ... #Pharmacology #Apixaban ... #Rivaroxaban #Dabigatran
DOAC Cheat Sheet
 • Apixaban, Dabigatran, Edoxaban, Rivaroxaban
 • Renal Dosing
 • Common Drug interactions
 •
DOAC Cheat Sheet ... • Apixaban, Dabigatran ... , Edoxaban, Rivaroxaban ... • Renal Dosing ... DeLoughery @Bloodman #DOAC
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
PCC (Kcentra) - Heparin ... (Praxbind) - Apixaban ... Edoxaban (Lixiana), Rivaroxaban ... anticoagulation #doac ... #noac #pharmacology
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
anticoagulant dosing ... Clotmaster #VTE #DOAC ... #Bridging #Dosing ... Anticoagulation #Dabigatran #Apixaban ... #Rivaroxaban #Edoxaban
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
clotting #INR #heparin ... #LMWH #NOAC #warfarin ... #coumadin #rivaroxaban ... #Xarelto #apixaban
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
anticoagulant (e.g. rivaroxaban ... - Rivaroxaban ... #LMWH #UFH #DOAC ... #Dabigatran #Apixaban ... #NOAC #Mechanism
Warfarin to DOAC and DOAC to Warfarin Transitions 

Here are a couple of charts to help
Warfarin to DOAC ... and DOAC to Warfarin ... for easier dosing ... Quick tip: apixaban ... Rivaroxaban is <
Choice of anticoagulant for treatment of pulmonary embolism
 • Malignancy - LMWH
 • To avoid parenteral
; apixaban • Once ... oral therapy - Rivaroxaban ... edoxaban; VKA • Hepatic ... with creatinine clearance ... Gl bleed - VKA, apixaban
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
Molecular Weight Heparin ... Xa inhibitors - Apixaban ... , rivaroxaban - ... #medications #doac