7 results
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Primary Routes of Clearance ... Anticoagulant Agents Warfarin ... Hepatic, 0% Renal Apixaban ... #Pharmacology # ... Clearance #oral
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... : Apixaban (25% ... renal clearance ... Anticoagulation #Hematology ... #Pharmacology #
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Reversal Agents - Warfarin ... (Praxbind) - Apixaban ... anticoagulation #doac ... #noac #pharmacology ... #hematology #reversal
Warfarin to DOAC and DOAC to Warfarin Transitions 

Here are a couple of charts to help
Warfarin to DOAC ... and DOAC to Warfarin ... dosing and monitoring ... Quick tip: apixaban ... Anticoagulation #Pharmacology
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
anticoagulant dosing ... Clotmaster #VTE #DOAC ... Anticoagulation #Dabigatran #Apixaban ... #Loading #DVT #Pharmacology ... #Hematology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
For patients on warfarin ... recent creatinine clearance ... (calculated using ... inhibitor) • Apixaban ... Management #Treatment #pharmacology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
Managing warfarin ... #management #algorithm ... #pharmacology # ... decisionaid #cardiology #hematology ... #warfarin #dosing