12 results
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Primary Routes of Clearance ... of Oral Anticoagulant ... Hepatic, 80% Renal Edoxaban ... Hepatic, 35% Renal #DOAC ... #oral #anticoagulation
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... dosing and bridging ... Clotmaster #VTE #DOAC ... #Rivaroxaban #Edoxaban ... #Pharmacology #Hematology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... Apixaban (25% renal clearance ... if CrCl < 50) Edoxaban ... @Bloodman #DOAC ... Anticoagulation #Hematology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
Currently, edoxaban ... direct-acting oral ... for appropriate dosing ... Anticoagulation #Management ... #Hematology #Oncology
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
NOAC / DOAC Pharmacology ... Novel (or Direct) Oral ... #Prescribing #hematology ... #management #Direct ... #Oral #AntiCoagulant
Best practice recommendations for the diagnosis and treatment of adult patients experiencing traumatic brain injury during
traumatic brain injury during ... treatment with oral ... Brain #Injury #NOAC ... #DOAC #Management
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Perioperative Management ... direct acting oral ... recent creatinine clearance ... (calculated using ... ) • Apixaban, Edoxaban
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... : • Apixaban, Edoxaban ... not available #DOAC ... #Oral #anticoagulant ... #hematology #management
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
**Edoxaban is initiated ... bleeding risk during ... DOAC, direct oral ... Anticoagulation #Management ... #Hematology #Oncology
Effect of Direct Oral Anticoagulants on Hemostatic Tests
Horizontal bars correspond to the approximate range of detectability
Effect of Direct Oral ... , apixaban and edoxaban ... thrombin time #doac ... #noac #anticoagulation ... #hematology #laboratory