28 results
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Diagnosis: • ... cells can indicate disease ... Scoring system: DDX ... microglobulin Treatment ... workup #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... mass • Rapidly rising ... plaques) AML Dx ... #Leukemia #Hematology ... #Oncology #Diagnosis
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... thrombocythemia), Autoimmune disease ... subsequent enhanced clearance ... #Management #treatment ... #hematology #differential
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
Disease Acute ... Supportive with treatment ... #SickleCell #Disease ... Hepatobiliary #hepatology ... #differential #diagnosis
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... • Avg age of DX ... DDX - Other causes ... Burns • Protein-losing ... hypogammaglobulinemia #immunology #hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
- Differential Diagnosis ... which are released during ... Colitis and Crohn’s Disease ... #Differential #Diagnosis ... #causes #hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
in those with CLD ... months without treatment ... underlying liver disease ... Failure #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Lymphocytic Leukemia (CLL ... chemotherapy for low-risk disease ... uw_IMresidency #CLL ... Leukemia #oncology #hematology ... #hemeonc #diagnosis
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Pain in Sickle Cell ... Disease Vaso-occlusive ... • XR, MRI to dx ... #differential #diagnosis ... #causes #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Management: • D/c all ... , Bivalirudin, DOAC ... re-challenge >100d after Dx ... #Management #Treatment ... #Hematology #HemeOnc