19 results
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
LMWH, warfarin, DOACs ... Advanced Liver Disease ... Post-partum • Acute DIC ... table #comparison #diagnosis ... #hematology #deficiency
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... thrombocythemia), Autoimmune disease ... subsequent enhanced clearance ... #Management #treatment ... #hematology #differential
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
helmet cells DDX ... • Severe Liver Disease ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
chronic liver disease ... and decreased clearance ... As a result of DIC ... LiverFailure #Hepatic #Hepatology ... #Laboratory #Diagnosis
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Avg age of DX ... late adulthood • Diagnosis ... DDX - Other causes ... Burns • Protein-losing ... hypogammaglobulinemia #immunology #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Diagnosis ... Cryofibrinogenemia DDX ... skin necrosis • DIC ... Cryofibrinogenemia #diagnosis ... hematology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
regarding the diagnosis ... and treatment of ... causes of liver disease ... including liver and hematologic ... #management #hepatology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
setting of liver disease ... intrinsic lung disease ... ) on room air Treatment ... #management #treatment ... #hepatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Thrombocytopenia (HIT) - Diagnosis ... , Bivalirudin, DOAC ... re-challenge >100d after Dx ... #Management #Treatment ... #Hematology #HemeOnc
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
kidney failure DDX ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology