13 results
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Primary Routes of Clearance ... of Oral Anticoagulant ... Hepatic, 80% Renal Edoxaban ... Hepatic, 35% Renal #DOAC ... #oral #anticoagulation
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... dosing and bridging ... Clotmaster #VTE #DOAC ... #Anticoagulation ... #Rivaroxaban #Edoxaban
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... Apixaban (25% renal clearance ... if CrCl < 50) Edoxaban ... OralAnticoagulant #Anticoagulation ... Rivaroxaban #Dabigatran #Edoxaban
Comparison of oral anticoagulant agents (DOACS + Warfarin)

Reference: ENLS 2017 Pharmacotherapy. Neurocritical Care Journal.

#DOAC #Dosing #Oral
Comparison of oral ... anticoagulant agents (DOACS ... #DOAC #Dosing #Oral ... #Anticoagulation
DOAC Cheat Sheet
 • Apixaban, Dabigatran, Edoxaban, Rivaroxaban
 • Renal Dosing
 • Common Drug interactions
 •
DOAC Cheat Sheet ... Apixaban, Dabigatran, Edoxaban ... Rivaroxaban • Renal Dosing ... #anticoagulation ... #CheatSheet #dosing
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
Currently, edoxaban ... direct-acting oral ... for appropriate dosing ... direct-acting oral ... Cancer #Algorithm #Anticoagulation
Oral Anticoagulation - VTE and DVT Bridging

- Amelia Furbish PharmD Student @ https://www.instagram.com/happypillsrx/

#DOAC #Oral #Anticoagulant #VTE
Oral Anticoagulation ... happypillsrx/ #DOAC ... #Oral #Anticoagulant ... DVT #Bridging #Dosing
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
patients on chronic anticoagulation ... direct acting oral ... recent creatinine clearance ... (calculated using ... ) • Apixaban, Edoxaban
Warfarin to DOAC and DOAC to Warfarin Transitions 

Here are a couple of charts to help
Warfarin to DOAC ... and DOAC to Warfarin ... for easier dosing ... Edoxaban is <2.5 ... Transitioning #Anticoagulation
Choice of anticoagulant for treatment of pulmonary embolism
 • Malignancy - LMWH
 • To avoid parenteral
• Once a day oral ... - Rivaroxaban; edoxaban ... with creatinine clearance ... decisionaid #vte #anticoagulation