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anticoagulation pharmacology hematology management noac vte algorithm anticoagulant apixaban cancer cheatsheet malignancy oncology rivaroxaban aptt bridging ckd dvt laboratory loading
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents Warfarin - 100% Hepatic, 0% Renal Apixaban
Primary Routes of Clearance ... of Oral Anticoagulant ... Hepatic, 25% Renal Dabigatran ... Hepatic, 80% Renal Edoxaban ... Hepatic, 35% Renal #DOAC
Oral anticoagulant dosing and bridging for VTE - Dr. Joseph Shatzel @Clotmaster #VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... dosing and bridging ... Clotmaster #VTE #DOAC ... Anticoagulation #Dabigatran ... #Rivaroxaban #Edoxaban
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing Renal Dosing: Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... Apixaban (25% renal clearance ... patients 5mg bid Dabigatran ... if CrCl < 50) Edoxaban ... #Edoxaban #NOAC
DOAC Cheat Sheet • Apixaban, Dabigatran, Edoxaban, Rivaroxaban • Renal Dosing • Common Drug interactions •
DOAC Cheat Sheet ... • Apixaban, Dabigatran ... , Edoxaban, Rivaroxaban ... • Renal Dosing ... DeLoughery @Bloodman #DOAC
Warfarin to DOAC and DOAC to Warfarin Transitions Here are a couple of charts to help
Warfarin to DOAC ... and DOAC to Warfarin ... for easier dosing ... : apixaban and dabigatran ... Edoxaban is <2.5
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis. Currently, edoxaban and rivaroxaban are the only
Currently, edoxaban ... direct-acting oral ... being stronger for edoxaban ... for appropriate dosing ... direct-acting oral
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 Perioperative Management of DOACs Problem: ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
direct acting oral ... recent creatinine clearance ... (calculated using ... of Therapy • Dabigatran ... ) • Apixaban, Edoxaban
DOAC Reversal Emergency surgery or urgent procedure Stop anticoagulant treatment; volume resuscitation and transfusion as needed Antidotes: • Apixaban,
DOAC Reversal Emergency ... : • Apixaban, Edoxaban ... modified factor Xa • Dabigatran ... not available #DOAC ... #Oral #anticoagulant
Effect of Direct Oral Anticoagulants on Hemostatic Tests Horizontal bars correspond to the approximate range of detectability
Effect of Direct Oral ... concentrations of dabigatran ... , apixaban and edoxaban ... thrombin time #doac ... #noac #anticoagulation
Treatment algorithm for VTE in Malignancy (A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
**Edoxaban is initiated ... bleeding risk during ... DOAC, direct oral ... #DOAC #VTE #Malignancy
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