7 results
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Primary Routes of Clearance ... of Oral Anticoagulant ... Hepatic, 0% Renal Apixaban ... Hepatic, 80% Renal Edoxaban ... Hepatic, 35% Renal #DOAC
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... dosing and bridging ... Clotmaster #VTE #DOAC ... Anticoagulation #Dabigatran #Apixaban ... #Rivaroxaban #Edoxaban
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
: Apixaban (25% ... renal clearance ... if CrCl < 50) Edoxaban ... #Pharmacology #Apixaban ... Rivaroxaban #Dabigatran #Edoxaban
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
Currently, edoxaban ... direct-acting oral ... for appropriate dosing ... direct-acting oral ... #DOAC #VTE #Malignancy
Choice of anticoagulant for treatment of pulmonary embolism
 • Malignancy - LMWH
 • To avoid parenteral
pulmonary embolism • Malignancy ... - Rivaroxaban; apixaban ... • Once a day oral ... - Rivaroxaban; edoxaban ... with creatinine clearance
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
direct acting oral ... recent creatinine clearance ... (calculated using ... inhibitor) • Apixaban ... , Edoxaban, Rivaroxaban
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
algorithm for VTE in Malignancy ... **Edoxaban is initiated ... bleeding risk during ... DOAC, direct oral ... #DOAC #VTE #Malignancy