13 results
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
of Oral Anticoagulant ... Hepatic, 80% Renal Edoxaban ... Hepatic, 35% Renal #DOAC ... #Pharmacology # ... Clearance #oral
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... dosing and bridging ... Clotmaster #VTE #DOAC ... #Rivaroxaban #Edoxaban ... #Loading #DVT #Pharmacology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... Apixaban (25% renal clearance ... if CrCl < 50) Edoxaban ... @Bloodman #DOAC ... Anticoagulation #Hematology #Pharmacology
Comparison of oral anticoagulant agents (DOACS + Warfarin)

Reference: ENLS 2017 Pharmacotherapy. Neurocritical Care Journal.

#DOAC #Dosing #Oral
Comparison of oral ... anticoagulant agents (DOACS ... #DOAC #Dosing #Oral ... Comparison #Table #Pharmacology
DOAC Cheat Sheet
 • Apixaban, Dabigatran, Edoxaban, Rivaroxaban
 • Renal Dosing
 • Common Drug interactions
 •
DOAC Cheat Sheet ... Apixaban, Dabigatran, Edoxaban ... Rivaroxaban • Renal Dosing ... DeLoughery @Bloodman #DOAC ... #ckd #pharmacology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
Currently, edoxaban ... direct-acting oral ... being stronger for edoxaban ... for appropriate dosing ... direct-acting oral
Oral Anticoagulation - VTE and DVT Bridging

- Amelia Furbish PharmD Student @ https://www.instagram.com/happypillsrx/

#DOAC #Oral #Anticoagulant #VTE
Oral Anticoagulation ... happypillsrx/ #DOAC ... #Oral #Anticoagulant ... DVT #Bridging #Dosing ... #Pharmacology
Warfarin to DOAC and DOAC to Warfarin Transitions 

Here are a couple of charts to help
Warfarin to DOAC ... and DOAC to Warfarin ... for easier dosing ... Edoxaban is <2.5 ... Anticoagulation #Pharmacology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
direct acting oral ... recent creatinine clearance ... (calculated using ... ) • Apixaban, Edoxaban ... Management #Treatment #pharmacology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... : • Apixaban, Edoxaban ... not available #DOAC ... #Oral #anticoagulant ... hematology #management #pharmacology