10 results
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
NOAC / DOAC Pharmacology ... Novel (or Direct) Oral ... • Apixaban • Dabigatran ... #Prescribing #hematology ... management #Direct #Oral
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Primary Routes of Clearance ... of Oral Anticoagulant ... Hepatic, 25% Renal Dabigatran ... Hepatic, 35% Renal #DOAC ... #oral #anticoagulation
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... dosing and bridging ... Clotmaster #VTE #DOAC ... Anticoagulation #Dabigatran ... #Pharmacology #Hematology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... Apixaban (25% renal clearance ... patients 5mg bid Dabigatran ... Anticoagulation #Hematology ... #Rivaroxaban #Dabigatran
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
direct-acting oral ... anticoagulants (DOACs ... for appropriate dosing ... direct-acting oral ... Anticoagulation #Management #Hematology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Management of DOACs ... direct acting oral ... recent creatinine clearance ... (calculated using ... of Therapy • Dabigatran
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... modified factor Xa • Dabigatran ... not available #DOAC ... #Oral #anticoagulant ... #hematology #management
Effect of Direct Oral Anticoagulants on Hemostatic Tests
Horizontal bars correspond to the approximate range of detectability
Effect of Direct Oral ... concentrations of dabigatran ... thrombin time #doac ... #noac #anticoagulation ... #hematology #laboratory
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
bleeding risk during ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... Anticoagulation #Management #Hematology
Esophageal Atresia and Tracheoesophageal Fistula- An infant had an apneic episode at birth and received positive-pressure
delivery room during ... Owing to the infant ... ’s copious oral ... the esophagus (arrow ... #NEJM #clinical