11 results
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Primary Routes of Clearance ... of Oral Anticoagulant ... Hepatic, 25% Renal Dabigatran ... #Pharmacology #Clearance ... #oral #anticoagulation
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
NOAC / DOAC Pharmacology ... Novel (or Direct) Oral ... • Apixaban • Dabigatran ... Prescribing #hematology #management ... #Direct #Oral #
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... Renal Dosing ... Apixaban (25% renal clearance ... patients 5mg bid Dabigatran ... #Rivaroxaban #Dabigatran
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... dosing and bridging ... Clotmaster #VTE #DOAC ... #Bridging #Dosing ... Anticoagulation #Dabigatran
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Oral Anticoagulation ... Management Cheat ... Warfarin, Apixaban, Dabigatran ... - Resume #Oral ... Anticoagulant #DOAC
Best practice recommendations for the diagnosis and treatment of adult patients experiencing traumatic brain injury during
traumatic brain injury during ... treatment with oral ... Brain #Injury #NOAC ... #DOAC #Management
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Perioperative Management ... direct acting oral ... recent creatinine clearance ... (calculated using ... of Therapy • Dabigatran
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
direct-acting oral ... anticoagulants (DOACs ... for appropriate dosing ... direct-acting oral ... Anticoagulation #Management
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... modified factor Xa • Dabigatran ... not available #DOAC ... #Oral #anticoagulant ... #hematology #management
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
bleeding risk during ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... Anticoagulation #Management