35 results
Acromegalic Hand: Markedly enlarged hand resulting from excess growth hormone. For reference
purposes, the comparison hand is
Acromegalic Hand ... Markedly enlarged hand ... the comparison hand ... #Photo #Acromegaly ... #Acromegalic #Hand
Cutis Verticis Gyrata: Idiopathic development of excess folds and furrows within the skin of the head.
Associated
furrows within the skin ... mental retardation, acromegaly ... Images #Clinical ... Verticis #Gyrata #Photo ... #UCSDH
Sclerodactyly: Diffuse thickening of the skin on the hands, in this case due to Scleroderma. 
Note
thickening of the skin ... on the hands, in ... Catalog of Clinical ... Images #Clinical ... #Photo #Dermatology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
clinical findings ... the same pathophysiology ... • Enlarged hands ... Overproduction #diagnosis ... #signs #symptoms
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... - Giantism or acromegaly ... , widening of hands ... tunnel, OSA, Incr skin ... endocrinology #pathophysiology
CREST Syndrome: Pathogenesis and Clinical Findings

CALCINOSIS (BB-sized, hard nodules in fingers)
RAYNAUD'S Phenomenon
ESOPHAGEAL DYSMOTILITY
SCLERODACTYLY (thickening and tightening
Clinical Findings ... tightening of skin ... TELANGIECTASIA (In face, hands ... #Diagnosis #Signs ... #Symptoms
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Acromegaly - Diagnosis ... GrepMed Handbook Clinical ... macrognathia), ↑ hand ... , hair growth, skin ... tags, skin thickening
Psoriasis: Chronic, idiopathic condition that leads to swelling, redness, and scaling of the skin.

Charlie Goldberg, M.D.
scaling of the skin ... Images #Clinical ... #Photo #Dermatology ... SkinRash #Psoriasis #Hands ... #Scaling #UCSDH
Reactive Arthritis
 • Inflammation of joints (commonly large joints)
    - Asymmetric Oligoarthritis: Joint
Transient • Skin ... keratotic lesions on hands ... ReactiveArthritis #pathophysiology ... #diagnosis #signs ... #symptoms
Cubital Tunnel Syndrome: Pathogenesis and clinical findings

 • Paresthesia of 5th and medial half of 4th
clinical findings ... awakening • Medial hand ... CubitalTunnel #Syndrome #Diagnosis ... #pathophysiology ... #signs #symptoms