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Vasopressors and Inotropes - Pharmacology Summary Vasopressors Phenylephrine (alpha-1) • Increases BP, SVR • Risk of reflex bradycardia
Increases BP, SVR, CO ... first agent in shock ... • Higher doses cause ... line in septic shock ... cAMP/cGMP • Causes
Shock - Pathophysiology Inadequate tissue perfusion to meet O2, nutrient requirements 1. Distributive Shock 2. Hypovolemic Shock 3. Cardiogenic
Shock - Pathophysiology ... Distributive Shock ... Hypovolemic Shock ... differential #diagnosis #algorithm ... #causes
Shock - Differential Diagnosis Framework MAP = CO x SVR Hypovolemic (↓ Intravascular volume): • Hemorrhage, dehydration due
Shock - Differential ... Framework MAP = CO ... third-spacing • ↓ CO ... findings based on cause ... uw_IMresidency #Shock
Shock Classification and Differential Diagnosis SHOCK • MAP <65, SBP <90, drop in SBP > 40 •
Shock Classification ... Differential Diagnosis SHOCK ... Distributive: • High CO ... Cardiogenic: • Low CO ... Sophia_Hayes_MD #Shock
Shock - Differential Diagnosis Framework - MAP <65. SBP <90, drop in SBP > 40 -
Shock - Differential ... Lactate > 1.5 High CO ... Cord Injury Low CO ... Dehydration Shock ... #criticalcare #algorithm
Shock - Differential Diagnosis Algorithm Warm Extremities - Distributive Shock - Low JVP
Shock - Differential ... Diagnosis Algorithm ... - Distributive Shock ... Differential #Diagnosis #Algorithm ... #causes
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Shock Overview ... - Low CO and therefore ... - Low CO and therefore ... - Low CO and therefore ... #differential #causes
Common Vasopressors and Inotropes Norepinephrine (NE) - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
: Distributive shock ... ), Cardiogenic shock ... (mild ↑CO) - Side ... , Shock where ↑ ... Bradyarrhythmias, Some cases
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Shock Overview ... - Low CO and therefore ... - Low CO and therefore ... - Low CO and therefore ... #differential #causes
Causes, classification and compensatory responses to shock. Shock can be caused by any pathological process that leads
Causes, classification ... compensatory responses to shock ... Shock can be caused ... The cause of shock ... #Differential #Causes
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