3001 results
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
Increases BP, SVR, CO ... first agent in shock ... • Higher doses cause ... line in septic shock ... cAMP/cGMP • Causes
Shock - Differential Diagnosis Framework
MAP = CO x SVR
Hypovolemic (↓ Intravascular volume):
 • Hemorrhage, dehydration due
Shock - Differential ... Framework MAP = CO ... third-spacing • ↓ CO ... findings based on cause ... uw_IMresidency #Shock
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Shock Overview ... - Low CO and therefore ... - Low CO and therefore ... - Low CO and therefore ... #differential #causes
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Shock Overview ... - Low CO and therefore ... - Low CO and therefore ... - Low CO and therefore ... #differential #causes
Shock Classification and Differential Diagnosis
SHOCK
 • MAP <65, SBP <90, drop in SBP > 40
 •
Shock Classification ... Differential Diagnosis SHOCK ... Distributive: • High CO ... Cardiogenic: • Low CO ... Sophia_Hayes_MD #Shock
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
: Distributive shock ... ), Cardiogenic shock ... (mild ↑CO) - Side ... , Shock where ↑ ... Bradyarrhythmias, Some cases
Causes, classification and compensatory responses to shock.

Shock can be caused by any pathological process that leads
Causes, classification ... compensatory responses to shock ... Shock can be caused ... The cause of shock ... #Differential #Causes
Approach to Undifferentiated Shock - OnePager Summary
Shock occurs when there is inadequate blood flow (CO) &
Undifferentiated Shock ... OnePager Summary Shock ... inadequate blood flow (CO ... Pump Problem (↓ CO ... may develop low CO
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Shock - Differential ... Lactate > 1.5 High CO ... Cord Injury Low CO ... Dehydration Shock ... Sophia_Hayes_MD #Shock
Shock - Pathophysiology 
Inadequate tissue perfusion to meet O2, nutrient requirements
1. Distributive Shock
2. Hypovolemic Shock
3. Cardiogenic
Shock - Pathophysiology ... Distributive Shock ... Hypovolemic Shock ... Cardiogenic Shock ... diagnosis #algorithm #causes