1098 results
Mechanism of Action of Bile Acid Sequestrants
Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Pool → ↑ HMG-CoA ... sequestration #pathophysiology
Allergic Rhinitis: Pathogenesis and clinical findings

1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
Cells -> lgE Abs coat ... Rhinitis #Rhinorrhea #pathophysiology
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... Pathway Activation (C3a ... and C5a) -> Anaphylatoxins ... Vasculitis #HUV #Pathophysiology
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
fragment bind B cell co-receptor ... Opsonization: Abs coat ... Humoral #Immunity #pathophysiology
Coarctation of Aorta (CoA) & Interrupted Aortic Arch (IAA)
 • Prevalence
 • Anatomy of CoA
 •
Coarctation of Aorta (CoA ... • Anatomy of CoA ... Associated Lesions with CoA ... Management & Outcome of CoA ... Coarctation #Aorta #CoA
Cushing's Reflex - Pathophysiology
HYPERTENSION with a reflex BRADYCARDIA
 → ↑ ICP 
 → ↓ CBF
 →
Cushing's Reflex - Pathophysiology ... → ↑ Cerebral [CO2 ... Cushings #Reflex #Pathophysiology
Antiplatelet Drugs and their Actions

- Amy Chung, MD, MSc
@AmyChung

#Antiplatelet #Medications #Pharmacology #Pathophysiology #Drugs #Agents #COX #GIIbIIIa
#Pharmacology #Pathophysiology ... Drugs #Agents #COX
Arachidonic acid pathway and drugs which affect it.

#Pharmacology #Pathophysiology #ArachidonicAcid #Pathways #COX #Prostaglandins #Prostacyclins #Leukotrienes #Synthesis

**
#Pharmacology #Pathophysiology ... ArachidonicAcid #Pathways #COX
Crystalloid pH, Contents and Costs Compared
Plasma	pH 7.4
Normal Saline	pH 5.5*	
Ringer’s Lactate pH 6.5	
Plasmalyte A pH 6.5	
Coca-cola pH
Plasmalyte A pH 6.5 Coca-cola
Heme Synthesis Pathway
Enzymes
1. ALA Synthase
2. ALA Dehydratase
3. Porphobilinogen deaminase
4. UP Ill Synthase
5. UP Ill Decarboxylase
6. Coproporphyrinogen
- James Dazhe Cao ... Synthesis #Pathway #pathophysiology