11 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Coagulation Cascade ... and Anticoagulant ... #Anticoagulants ... #Pharmacology #Pathophysiology ... Mechanisms #DOAC #Hematology
Coagulation Cascade - Actions of Anticoagulants
 • Heparin: Unfractionated heparin, Enoxaparin, Daltaparin
 • Fondaparinux
 • Direct
Coagulation Cascade ... - Actions of Anticoagulants ... : Rivaroxaban, Apixaban ... EricsMedicalLectures/ #Coagulation ... #Cascade #Anticoagulants
Coagulation and kinin pathways

#Pharmacology #Pathophysiology #Coagulation #Kinin #Pathways #Cascade #Anticoagulants #Antithrombotics #Thrombolytics
Coagulation and ... #Pharmacology #Pathophysiology ... #Coagulation #Kinin ... #Pathways #Cascade ... #Anticoagulants
Coagulation cascade and anticoagulants 

Satyendra Dhar MD, @DharSaty

#coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
Coagulation cascade ... and anticoagulants ... @DharSaty #coagulation ... heparin #warfarin #apaxiban
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
#Coagulation #Cascade ... diagnosis #models #hematology ... #pathophysiology ... anticoagulation #anticoagulant ... thrombin #inhibitor #Apixaban
Hemostasis Physiology

The blood's response to blood vessel injury can be viewed as four interrelated steps. 
Roman
numerals refer to coagulation ... #Hemostasis #Pathophysiology ... #Coagulation #Cascade ... #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Intravascular Coagulation ... protein C and S Pathophysiology ... is simultaneous coagulation ... Reduction of pro/anticoagulants ... treatment #management #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
- Rivaroxaban, apixaban ... heparin - Other anticoagulants ... intravascular coagulation ... #differential #hematology ... #coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
inhibitor of a coagulation ... integrity Clotting cascade ... intravascular coagulation ... deficiency • Anticoagulant ... Differential #Diagnosis #Hematology
THROMBOELASTOGRAPHY (TEG)
General Principle
• A small cuvette is rotated to simulate sluggish venous flow and stimulate clot
problems with coagulation ... cascade and platelet ... #CriticalCare #Hematology ... #Interpretation