5 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Coagulation Cascade ... and Anticoagulant ... #Anticoagulants ... #Medications #Pharmacology ... #Pathophysiology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
#Coagulation #Cascade ... #clot #PT #PTT ... #diagnosis #models ... #hematology #pathophysiology ... anticoagulation #anticoagulant
Review of the Coagulation Cascade
Traditional Model:
 • Parallel extrinsic and intrinsic pathways.
Contemporary Model:
 • 4 key
Review of the Coagulation ... Cascade Traditional ... common pathway): Thrombin ... #Cascade #diagnosis ... #pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Increased thrombin ... protein C and S Pathophysiology ... /INR: ↑ • PTT: ... Reduction of pro/anticoagulants ... #diagnosis #causes
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
- Differential Diagnosis ... inhibitor of a coagulation ... integrity Clotting cascade ... warfarin, direct thrombin ... #Differential #Diagnosis