1998 results
Thyroid Goiter on Physical Exam

Mother and daughter both presenting with thyroid goiters caused by iodine deficiency.
Thyroid Goiter on ... presenting with thyroid ... goiters caused by iodine ... #PhysicalExam #iodine ... endocrinology #clinical
Thyroid Disorders - Differential Diagnosis Algorithm
Hypothyroidism:
 • Hasimoto’s
 • Radioactive Iodine 
 • Hypopituitarism
 • Iodine
Thyroid Disorders ... • Radioactive Iodine ... Hypopituitarism • Iodine ... @AmyChung #Thyroid
Laboratory Evaluation of Patients for Thyroid Disease 
Hyperthyroidism:
 • Graves disease - TSH low; free T4
of Patients for Thyroid ... increased radioactive iodine ... uptake; thyroid ... uptake; thyroid ... concentrations of TSH and thyroid
Amiodarone Thyroid Complications
Amiodarone: 
 - iodine-rich, similar structure to T4, with half life up to 100d
Amiodarone Thyroid ... Amiodarone: - iodine-rich ... pts w/ latent thyroid ... dz: iodine load ... Wolff-Chaikoff effect (iodine
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
Hyperthyroidism Overview Clinical ... Toxicosis • Iodine ... with radioactive iodine ... Thionamide - Iodine ... • Radioactive iodine
Differentiation of Causes of Hyperthyroidism According to Pattern of Radionucleotide Uptake
Reduced uptake:
 • Thyroiditis
 • Exogenous
thyroxine • Iodine ... loading • Ectopic thyroid ... disease • Excess thyroid-stimulating ... #radioactive #iodine
Pharmaceutical Management of Hyperthyroidism / Thyroid Storm
Beta-Blockers 
• Decreases sympathetic hyperactivity 
• Partially blocks peripheral conversion
Hyperthyroidism / Thyroid ... Blocks synthesis of thyroid ... Blocks synthesis of thyroid ... • Teratogenic Iodine ... release of stored thyroid
Approach to the Diagnosis of Hyperthyroidism - Differential Diagnosis and Workup Algorithm

 • Secondary Hyperthyroidism (↑↔TSH,
Radioactive Iodine ... disease • Low iodine ... goiter Radioactive Iodine ... • Thyroiditis, Iodine ... • Exogenous thyroid
Graves' Disease Treatment
Thionamides (mainly methimazole)
 • Chance of remission in up to 2 years
 • No
2 years • No thyroid ... cost Radioactive Iodine
Approach to Thyroid Function Tests in the Evaluation of Hyperthyroidism
 • Low TSH, Low normal T4
Approach to Thyroid ... of pregnancy, critical ... symmetrically enlarged thyroid ... → Radioactive Iodine