11 results
Spectrum of Glomerular Diseases
Nephrotic - Mechanism:
 • Injury to podocytes
 • Changed architecture: Scanning. Deposition of
Spectrum of Glomerular ... Diseases Nephrotic ... • Injury to podocytes ... Deposition of matrix ... formation #Glomerular
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... but in severe cases ... Nephrotic yndrome—podocyte ... diabetes)) #Glomerular
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic ... the patient have glomerular ... hematuria (RBC casts ... #Nephritic #Nephrotic ... Syndrome #Comparison #Algorithm
Causes of Acute Kidney Injury - Differential Diagnosis Framework 
Pre-Renal
Post-Renal
Intrinsic Renal:
 • Tubules (ATN)
 • Glomerular:
Causes of Acute ... Tubules (ATN) • Glomerular ... : Nephrotic, Nephritic ... #KidneyInjury #Causes ... Differential #Diagnosis #Algorithm
This image shows glomerular tuft with overall intact architecture. Discrete masses of specular amyloid interrupt smooth
This image shows glomerular ... Discrete masses ... CapillaryLoop #glomerulus ... #amyloid #desposition ... #deposits #ElectronMicroscopy
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Differential Diagnosis Algorithm ... • Hereditary nephritis ... Immune-complex deposition ... and >3.5g/day (nephrotic ... #Causes
This image shows a glomerular tuft with overall intact architecture. Discrete masses of specular amyloid (long
image shows a glomerular ... Discrete masses ... arkanalabs #glomerulus ... #amyloid #desposition ... #deposits #ElectronMicroscopy
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Differential Diagnosis Algorithm ... • Drugs Glomerular ... • Protein deposition ... Differential #Diagnosis #Algorithm ... #Causes
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
dysmorphic RBC, RBC casts ... formation along glomerular ... • Complement deposition ... complement of lg deposition ... glomerulopathy, radiation nephritis
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... clusters because nephritic ... Nephrocalcinosis causes ... #Algorithm #differential ... #proteinuria #nephrotic