9 results
Spectrum of Glomerular Diseases
Nephrotic - Mechanism:
 • Injury to podocytes
 • Changed architecture: Scanning. Deposition of
Spectrum of Glomerular ... Diseases Nephrotic ... • Injury to podocytes ... other elements Nephritic ... formation #Glomerular
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... Nephrotic yndrome—podocyte ... 10 (eg direct podocyte ... damage) or 20 (podocyte ... diabetes)) #Glomerular
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic ... /nephritic syndromes ... the patient have glomerular ... #Nephritic #Nephrotic ... Syndrome #Comparison #Algorithm
Causes of Acute Kidney Injury - Differential Diagnosis Framework 
Pre-Renal
Post-Renal
Intrinsic Renal:
 • Tubules (ATN)
 • Glomerular:
Tubules (ATN) • Glomerular ... : Nephrotic, Nephritic ... Differential #Diagnosis #Algorithm
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Differential Diagnosis Algorithm ... • Calculi Glomerular ... epithelial side of glomerular ... endothelial side of glomerular ... and >3.5g/day (nephrotic
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... presenting with overt glomerular ... Cytomegalovirus; GBM = glomerular ... #Algorithm #differential ... #diagnosis #glomerular
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
The gout drug pegloticase ... filtered in the glomerulus ... #Homeostasis #Gout ... #Pathophysiology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... inversely related to glomerular ... rate by tubulo-glomerular ... Differential #Diagnosis #Algorithm ... #Pathophysiology
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
nephron -> Decr Glomerular ... Hyperuricemia #Pathophysiology ... Complications #Gout