14 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... Proteinuria often ... Nephrotic yndrome—podocyte ... diabetes)) #Glomerular ... #Classification
Spectrum of Glomerular Diseases
Nephrotic - Mechanism:
 • Injury to podocytes
 • Changed architecture: Scanning. Deposition of
Spectrum of Glomerular ... Diseases Nephrotic ... • Injury to podocytes ... formation #Glomerular ... #Diseases #differential
Glomerular Diseases - Spectrum
 - Insidious vs Acute
 - Nephritic (hypertension, hematuria, renal failure) vs Nephrotic
Glomerular Diseases ... renal failure) vs Nephrotic ... (Heavy proteinuria ... Mehr @poyanmehr #Glomerular ... Diseases #Spectrum #differential
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic ... hematuria and/or proteinuria ... the patient have glomerular ... #Nephritic #Nephrotic ... Syndrome #Comparison #Algorithm
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
with evidence of glomerular ... disease (hematuria, proteinuria ... immune deposits in glomeruli ... post-infectious GN Anti-Glomerular ... #Differential #
Causes of Acute Kidney Injury - Differential Diagnosis Framework 
Pre-Renal
Post-Renal
Intrinsic Renal:
 • Tubules (ATN)
 • Glomerular:
Kidney Injury - Differential ... Tubules (ATN) • Glomerular ... : Nephrotic, Nephritic ... KidneyInjury #Causes #Differential ... #Diagnosis #Algorithm
This image shows scanning EM of a proteinuric glomerulus with capillary loop showing widening and partial
of a proteinuric ... glomerulus with ... interdigitating podocyte ... arkanalabs #glomerulus ... ElectronMicroscopy #SEM
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Diagnosis Algorithm ... • Calculi Glomerular ... epithelial side of glomerular ... endothelial side of glomerular ... range) proteinuria
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
presenting with overt glomerular ... Cytomegalovirus; GBM = glomerular ... #Algorithm #differential ... #diagnosis #glomerular ... #proteinuria #nephrotic
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
SLE Hallmark = proteinuria ... therapy Goal: proteinuria ... by 12 months Classification ... Focal LN (<50% of glomeruli ... Diffuse LN (>50% of glomeruli