Colchicine chronic clinical - GrepMed

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Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
• Young

association • M > F Clinical ... Behcet syndrome (Clinical ... mucocutaneous lesions-Colchicine ... Recurrent and chronic

Medications for Prevention of Chronic Gout
Colchicine (Colcrys)
Pegloticase (Krystexxa)
Probenecid
Xanthine oxidase inhibitors:
- Allopurinol (Zyloprim)
- Febuxostat (Uloric)
#Chronic

Prevention of Chronic ... Gout Colchicine ... Febuxostat (Uloric) #Chronic

Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
• RHABDOMYOLYSIS

statins, fibrates, colchicine ... immobility • Critical ... exercise Subacute to Chronic ... Statins, fibrates, colchicine ... daptomycin - Chronic

Approach to Gout
Diagnosis: r/o septic arthritis! Needle-shaped, negative birefringent crystals
Treatment:
• Weight loss, diet, d/c culprit

, Anakinra • Colchicine ... : Acute and chronic ... treatment • Chronic

Medications for Treatment of Acute Gout
- NSAIDs
- Colchicine (Colcrys)
- Corticosteroids
#Acute #Gout #Medications #Treatment

- NSAIDs - Colchicine

Gout Management in CKD
• Colchicine
• NSAID
• Glucocorticoid
• ACTH
• Interleukin-1 Inhibitors

#Gout #Management

Management in CKD • Colchicine

Diagnosis and Management of Hypocomplementemic Urticarial Vasculitis (HUV)

Diagnosis of HUV
1) Chronic urticaria
2) Leukocytoclastic vasculitis
3)

Diagnosis of HUV 1) Chronic ... Hydroxychloroquine, colchicine

Colchicine Toxicity
Naturally-occurring plant alkaloid [Autumn Crocus and Glory Lilly]
2-24 hrs
• Severe GI distress

Colchicine Toxicity ... still alive) #Colchicine

$Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:$

• Prevention: Colchicine ... Arthritis: • Colchicine ... topical steroids + colchicine

Lichen Simplex Chronicus: Thickened, red, puritic patch of skin resulting from chronic rubbing
and scratching.

Charlie Goldberg,

Lichen Simplex Chronicus ... resulting from chronic ... UCSD Catalog of Clinical ... Images #Clinical ... Lichen #Simplex #Chronicus

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