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differential anaphylaxis management hematology syndrome algorithm arthritis autoimmune behcet causes criteria disease disorders eosinophil eosinophilia heat heatstroke illness immunology leukostasis
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
Signs / Symptoms ... -> Circulatory collapse ... seizures) - Cardiac ... pathophysiology #immunology #diagnosis ... #signs #symptoms
Manifestations of Anaphylaxis by Body System Dermatologic/mucosal - Eyes: periorbital swelling/erythema, injected conjunctiva, tears - Oral mucosa:
cyanosis, respiratory collapse ... leads, cyanosis, cardiac ... cessation of play #Diagnosis ... #Allergy #Signs ... #Symptoms #Anaphylaxis
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 Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
causes are asthma, allergy ... organ-specific signs ... or symptoms (eg ... #Differential #diagnosis ... #hematology #eosinophilia
Clinical manifestations of anaphylaxis. Neurological (<15%): Dizziness, syncope, seizures, Confusion, impending doom. headache Angioedema: Lips, tongue, orbit,
, hypotension, cardiac ... #anaphylaxis #signs ... #symptoms #diagnosis ... #criteria #allergy
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
skin thickening Signs ... and Symptoms: ... • Cardiac: myocardial ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
WBC >100k, + lab signs ... lethargy, hematuria, cardiac ... with tetany or cardiac ... Syndrome #TLS #diagnosis ... #management #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... thrombosis, VTE) • Cardiac ... ) Differential Diagnosis ... #management #signs ... #symptoms #rheumatology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
- Differential Diagnosis ... Exercise Associated Collapse ... → Syncope • Signs ... /Symptoms: - Lightheadedness ... maintain adequate cardiac
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Rheumatoid Arthritis - Signs ... and Symptoms • ... Atherosclerosis • Cardiac ... #Symptoms #diagnosis ... #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... nose, tracheal collapse ... #Rheumatology
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