11 results
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
exposure to a likely allergen ... exposure to known allergen ... -> Circulatory collapse ... seizures) - Cardiac ... pathophysiology #immunology #diagnosis
Manifestations of Anaphylaxis by Body System

Dermatologic/mucosal

 - Eyes: periorbital swelling/erythema, injected conjunctiva, tears

 - Oral mucosa:
cyanosis, respiratory collapse ... leads, cyanosis, cardiac ... cessation of play #Diagnosis ... #Allergy #Signs ... #Symptoms #Anaphylaxis
Clinical manifestations of anaphylaxis. 
Neurological (<15%): Dizziness, syncope, seizures, Confusion, impending doom. headache
Angioedema: Lips, tongue, orbit,
, hypotension, cardiac ... arrest, Kounis syndrome ... anaphylaxis #signs #symptoms ... #diagnosis #criteria ... #allergy
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... lethargy, hematuria, cardiac ... with tetany or cardiac ... #TLS #diagnosis ... #management #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
meningitis), MCC CNS symptoms ... thrombosis, VTE) • Cardiac ... ) Differential Diagnosis ... #signs #symptoms ... #rheumatology #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... 5% of patients Cardiac ... Cytopenias • Cardiac ... Induced Lupus: • Symptoms ... #Rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... Presentation: Systemic Symptoms ... • Progressive symptoms ... nose, tracheal collapse ... #Rheumatology
Rheumatoid Arthritis - Signs and Symptoms
 • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans
 • Pulmonary:
Arthritis - Signs and Symptoms ... Atherosclerosis • Cardiac ... Thrombocytosis, Felty's syndrome ... Arthritis #RA #Signs #Symptoms ... #diagnosis #rheumatology
Fibromyalgia Symptoms
Cardinal Features:
 • Sleep disturbances: Insomnia, Frequent awakening, Non-restoring sleep
 • Pain: Generalized (head-to-toes), Described
Fibromyalgia Symptoms ... Cardinal Features ... Regional pain syndromes ... irritable bowel syndrome ... #diagnosis #rheumatology
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
ethnicities Symptoms ... + Nonspecific symptoms ... Complications: • Airway collapse ... vessel aneurysms • Cardiac ... Polychondritis #rheumatology