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diagnosis management syndrome cancer emergencies hemeonc oncologic algorithm apml arteritis chronic cirrhosis clarksons cll differential differentiation disease gca giantcell hepatology
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Oncologic Emergencies ... Diagnosis Framework HEMATOLOGIC ... neutrophil count < 500 cells ... shoulder pain, collateral ... Progressive decline in mental
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytes • Median ... Transformation to large cell ... transformation) Treatment ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... • Induce blast cell ... Imaging: CXR- pulmonary ... diagnosis #management #hematology ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Exposure to heavy metal ... factor (GCSF) treatments ... marrow studies Treatment ... Syndromes #diagnosis #hematology ... #oncology
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Clarkson’s Disease - Capillary ... published cases, Median ... filling +++ (risk of pulmonary ... Clarksons #Disease #Capillary ... #rheumatology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... syndrome): - Hematologic ... “big & sticky” cells ... ± tocilizumab; call ... renal failure, pulmonary
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... (GCA) Giant cell ... Involves large and medium ... of the steroid treatment ... Treatment of GCA
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
• Median age 50- ... Bone marrow Treatment ... Prognosis: • Median ... #Plasmacytoma #Oncology ... Diagnosis #Workup #Hematology
Hepatopulmonary Syndrome - Illness Script HPS is a pulmonary disorder of chronic liver disease characterized by a
Intrapulmonary capillary ... the left heart TREATMENT ... • No effective medical ... only definitive treatment ... cirrhosis #diagnosis #hepatology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
syndromes current treatment ... Because the median ... cardiovascular or pulmonary ... with repeated red cell ... #algorithm #hematology
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