13 results
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... Signs/Symptoms/Complications ... a scrotum #21HydroxylaseDeficiency ... #21OHD #pathophysiology ... #genetics #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... • Other rare causes ... diagnosis #signs #symptoms ... #endocrinology ... #pathophysiology
Hashitoxicosis

‘Leakage’ symptoms of active Hashimoto’s disease

- Hashitoxicosis (Htx) can occur during the initial hyperthyroid stage in
Hashitoxicosis ‘Leakage’ symptoms ... thyroiditis that causes ... ‘Leakage’ symptoms ... Hashitoxicosis #Hashimotos #Endocrinology ... #Diagnosis #Pathophysiology
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings

Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
the bladder Stress ... to Void - Weak Stream ... SUI or UUI not caused ... Incontinence #Mixed #Pathophysiology ... #Signs #Symptoms
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
out of cells may cause ... Signs/Symptoms/Complications ... Abdominal pain, nausea ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
over areas of stress ... inflammation tends to cause ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... without other cause ... ARDS to explain symptoms ... transfusion • Pathophysiology ... of (Acute resp distress
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
For pituitary masses ... Signs / Symptoms ... Headaches • Nausea ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Collapse: • Pathophysiology ... Syncope • Signs/Symptoms ... environmental heat stress ... Hyperventilation, Dizziness, Nausea ... differential #diagnosis #causes
Opioid Withdrawal: Clinical Findings and Complications
Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
Symptoms can take ... The somatic symptoms ... Gastrointestinal distress ... (nausea, vomiting ... Withdrawal #Opiate #Pathophysiology