9 results
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Passive neck flexion ... While the pathophysiology ... flexion occurs as ... despite severe disease ... #Meningitis #Clinical
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... extrapulmonary cases Clinical ... Signs/Symptoms: ... decreased reflexes Pathophysiology ... should be done in ALL
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of the clinical ... lateral sclerosis Pathophysiology ... Presentation: - Disease ... course of the disease ... neurology #diagnosis #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... Medium and large also ... : Pericarditis, ... Syndrome #diagnosis #management ... #signs #symptoms
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
weakness in the neck ... auricular papules Clinical ... had more severe disease ... renal carcinoma • Colon ... #diagnosis #management
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
papules and Gottron sign ... ) • Shawl sign ... pancreas, stomach, colon ... pancreas, stomach, colon ... Symptoms: • Pericarditis
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Rheumatologic symptoms • Pericarditis ... has five major clinical ... fungal stain of clinical ... Aspergillosis Pathophysiology ... Fungal #Diagnosis #Management
Cryptogenic Organizing Pneumonia - Illness Script

PATHOPHYSIOLOGY: Unknown trigger, reversible inflammatory/fibroproliferative process. Polypoid fibroblastic aggregates that plug
Illness Script PATHOPHYSIOLOGY ... Males=Females SIGNS ... DIAGNOSTICS: Clinical ... steroids for severe disease ... Pneumonia #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
• In all patients ... ▪ Autoimmune diseases ... Clinical Presentation ... • Common Signs ... Pathophysiology