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Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
New Potassium-Binding ... #Potassium #Binding ... #KBinders #Kayexelate ... #Comparison #Table
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... dose at weekly intervals ... #Hyperkalemia #medications ... #pharmacology #table ... #comparison #binders
Table 22 provides the characteristics of various phosphate-binding agents.
#Pharmacology #Nephrology #Phosphate #Phosphorus #Binders #Comparison #Table #Disadvantages
Table 22 provides ... various phosphate-binding ... Phosphate #Phosphorus #Binders ... #Comparison #Table
Drugs Implicated in Hemolytic Anemia
 • Hapten (Drug binding to RBC membrane): Penicillin, Cephalosporin, Tetracycline, Tolbutamide,
• Hapten (Drug binding ... drug-antibody complex binds ... Bloodman #Drugs #medications ... #pharmacology #table
Common Fungal Pathology 
 • Candida - Small yeast intermingled with pseudohyphae
 • Aspergillosis - Septate
with narrow based budding ... neoformans - Narrow- budding ... capsules UCSD Internal ... clinical #microscopy #table ... #atlas #key #comparison
Opioid Use Disorder Medications - Pharmacokinetics

Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
activity, high binding ... arrhythmia from QT interval ... the sublingual tablet ... Pharmacokinetics #Comparison ... #Table #Pharmacology
Sedative-Hypnotic Drugs
Benzodiazepines:
 - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
Antagonists: - Blocks binding ... Hypnotic #Drugs #medications ... #pharmacology #comparison ... #table
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... depress, ↑PR ↑QRS intervals ... Elimination (see Table ... STOP offending medications ... Treatments: • K-Binding
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
Metabolic syndrome • Medications ... ankles, knees, fingers ... • Nonspecific findings ... #CPPD #Gout #Comparison