14 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
New Potassium-Binding ... #Potassium #Binding ... KBinders #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... dose at weekly intervals ... necessary at 1-wk intervals ... #pharmacology #table ... #comparison #binders
Electrolyte imbalances are common findings in many diseases. The kidney is a principally responsible organ for
imbalances are common findings ... create a complex clinical ... #Hyponatremia #hypokalemia ... #hypercalcemia ... #electrolyte #algorithm
Common Fungal Pathology 
 • Candida - Small yeast intermingled with pseudohyphae
 • Aspergillosis - Septate
with narrow based budding ... capsules UCSD Internal ... Fungal #Pathology #clinical ... #microscopy #table ... #atlas #key #comparison
Adrenal Insufficiency Diagnosis Algorithm
Clinical features: 
 - Weight loss, anorexia, Weakness, fatigue, GI distress
 - Hypotension,
Insufficiency Diagnosis Algorithm ... Clinical features ... Hyponatremia, hyperkalemia ... eosinophilia Diagnostic findings ... (see algorithm)
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... depress, ↑PR ↑QRS intervals ... Elimination (see Table ... Treatments: • K-Binding ... #Hyperkalemia
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... : Hypovolemia, Hypervolemia ... Osmostat Stanford Internal ... differential #diagnosis #table
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... diuresis SCVMC Internal ... hematology #diagnosis #comparison ... #table
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
Clinically Significant ... Licorice - Causes hypokalemia ... - Increases QT interval ... - Increases QT interval ... pharmacology #DDI #table
Opioid Use Disorder Medications - Pharmacokinetics

Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
activity, high binding ... arrhythmia from QT interval ... the sublingual tablet ... Pharmacokinetics #Comparison ... #Table #Pharmacology