15 results
Antiarrhythmics - Vaughan Williams Classification
Class I (Ia, Ib, Ic) - Na+ Channel Blockade
 • Slows depolarization
Vaughan Williams Classification ... and prolongs PR interval ... • Prolongs QT interval ... and prolongs PR interval ... #Classes #cardiology
Hypokalemia - Differential Diagnosis
Poor Intake 
 - Starvation
 - Anorexia
GI Losses 
 - Vomiting / NG
Hypomagnesemia Internal ... Differential #Diagnosis #Low ... #Potassium #Table ... #Classification ... #Causes
Hypokalemia Differential Diagnosis Algorithm

Low intake 
• poor oral intake 

Renal loss 
• Medication 
• Hypomagnesemia 
•
Differential Diagnosis Algorithm ... Low intake ... Frameworks for Internal ... Differential #Diagnosis #Algorithm ... #Causes #Classification
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... depolarization • ↑ PR interval ... Duration) - ↑ QT interval ... velocity) - ↑ PR interval ... #Classes #pathophysiology
Hyperkalemia shortens repolarization; changes in the T wave provide the earliest clues to hyperpotassemia.
 - At
repolarization causes ... in conduction causes ... prolonged PR and QT intervals ... wave to produce classic ... Progression #Table
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Vaughan Williams Classification ... depolarization • ↑ PR interval ... Duration) - ↑ QT interval ... velocity) - ↑ PR interval ... #Classes #pathophysiology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Low Mean Corpuscular ... Chronic Disease (e.g ... #Anemia #MCV #Classification ... #Causes #Hematology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low ... GPA Stanford Internal ... differential #diagnosis #algorithm
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... normal volume-based algorithm ... Uosm <100): Renal Losses ... Osmostat Stanford Internal ... differential #diagnosis #table
Recurrent Polymorphic VT/Torsades de Pointes - Management Algorithm
Drugs that prolong QT interval:
 • Class 1a (quinidine,
Pointes - Management Algorithm ... that prolong QT interval ... • Adult: 0.5-5 mcg ... 1b (lidocaine)- case ... TDP #Management #Algorithm