8 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Rapidly Progressive ... three primary pathophysiologic ... staining): • Low Complement ... RPGN #Rapidly #Progressive ... differential #diagnosis #algorithm
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Complement activation ... Post-streptococcal glomerulonephritis ... Hypersensitivity #Types #Classification ... #Pathophysiology ... Diagnosis #Reactions #Table
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Differential Diagnosis Algorithm ... Hypotension • Shock ... Malignancy Rapidly Progressive ... Glomerulonephritis ... Differential #Diagnosis #Algorithm
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of ... they activate complement ... Post-streptococcal glomerulonephritis ... types #allergy #table ... #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
proteinuria, rapidly progressing ... - Necrotizing glomerulonephritis ... , pauci-immune glomerulonephritis ... against MPO • Complement ... #rheumatology #classification
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... system (node) with progression ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #differential #algorithm
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
dysfunction PATHOPHYSIOLOGY ... inflammation -> progressive ... - ↑ IgE, ↓ complement ... • Classification
6/02/2022 UPDATE: This assay is designed to detect non-variola orthopoxviruses, including monkeypox virus. It is not
2022-lab-advisory-CLARIFICATION-CDC_Publishes_Non-variola_Orthopoxvirus_PCR_Testing_Procedure ... should use this algorithm ... smallpox-diagnostic-algorithm-poster ... depending upon disease progression ... See table below