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diagnosis nephrology differential hypersensitivity allergy reactions rheumatology cardiology ecg ekg electrocardiogram kidney renal summary table vasculitis acute acuteglomerulonephritis allergic atrioventricular
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Hypersensitivity Types ... antigen, leading to complement ... Complement activation ... Post-streptococcal glomerulonephritis ... #Classification
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Membranoproliferative Glomerulonephritis ... (MPGN) AKA: Mesangiocapillary ... staining (lg + complement ... MGPN • Complement ... Membranoproliferative #Glomerulonephritis
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of types ... antigens, leading to complement ... they activate complement ... Post-streptococcal glomerulonephritis ... allergy #table #classification
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Membranoproliferative glomerulonephritis ... , type 1 (50%-80% ... ), type II (80-90% ... Post/pauci immune glomerulonephritis ... Hypocomplementemia #Low #Complement
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Kidney Injury - Classification ... Post-infectious glomerulonephritis ... prolonged prerenal AKI ... EricsMedicalLectures/ #AKI ... Kidney #Injury #Classification
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Hypersensitivity: Summary Type ... conjunctivitis Type ... Graves' Disease Type ... Post-infectious glomerulonephritis ... #Classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Skin ulcers - Glomerulonephritis ... Types: • Type ... • Type III Often ... • Low serum C4 complement ... #classification
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
Rapidly Progressive Glomerulonephritis ... autoAb against type ... staining #Glomerulonephritis ... #RPGN #Classification
Comprehensive pathogenesis of IgA Nephropathy (i.e Berger’s Disease). IgA Nephropathy is the most common cause of
common cause of Glomerulonephritis ... - What type of Hypersensitivity ... Relationship of complement ... AcuteGlomerulonephritis #Glomerulonephritis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Necrotizing glomerulonephritis ... , pauci-immune glomerulonephritis ... arthritis. (± glomerulonephritis ... against MPO • Complement ... #rheumatology #classification
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