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diagnosis fracture hypersensitivity nephrology rheumatology aliem allergy differential management ortho reactions ddxof renal supracondylar table vasculitis acuteglomerulonephritis algorithm allergic aortic
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Hypersensitivity Types ... antigen, leading to complement ... Complement activation ... Post-streptococcal glomerulonephritis ... #Classification
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Membranoproliferative Glomerulonephritis ... staining (lg + complement ... MGPN • Complement ... immune deposits on EM ... Membranoproliferative #Glomerulonephritis
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of types ... antigens, leading to complement ... they activate complement ... Post-streptococcal glomerulonephritis ... allergy #table #classification
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Membranoproliferative glomerulonephritis ... , type 1 (50%-80% ... ), type II (80-90% ... Post/pauci immune glomerulonephritis ... Hypocomplementemia #Low #Complement
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
Rapidly Progressive Glomerulonephritis ... autoAb against type ... staining on IF • No EM ... staining #Glomerulonephritis ... #RPGN #Classification
A System for Cerebrovascular Disease #Diagnosis #EM #Neuro #CVA #Stroke #Classification #Types #Frequency #Ddxof
Disease #Diagnosis #EM ... #CVA #Stroke #Classification ... #Types #Frequency
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Hypersensitivity: Summary Type ... conjunctivitis Type ... Graves' Disease Type ... Post-infectious glomerulonephritis ... #Classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Skin ulcers - Glomerulonephritis ... Types: • Type ... • Type III Often ... • Low serum C4 complement ... #classification
Supracondylar Fracture Classification - Type I: Non-displaced. Type II: Displaced with intact anterior cortex. Type III:
Supracondylar Fracture Classification ... Type II: Displaced ... Type III: Complete ... cortex) #Diagnosis #EM ... Flexion #Fracture #Classification
Aortic Dissection - Diagnosis and Management Summary • HPI: sudden onset, "tearing" chest pain, radiation to
Dissection protocol • Classification ... : - Type A ... aorta) - Type ... Management: • Type ... - MH/CCF/CWRU EM
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