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diagnosis differential rheumatology causes cryoglobulinemia cryoglobulins erythematosus gammopathy glomerulonephritis hypertension indications lupus malignancy management mgrs monoclonal progressive rapidly renal rpgn
Causes of Hypercalcemia due to increased Vitamin D levels • The BIG 3:
Causes of Hypercalcemia ... diseases: PR3+ vasculitis ... granuloma, BCG-associated ... hepatitis, Paraffin-associated ... differential #diagnosis #endocrinology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... Glomerulonephritis • With associated ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: ANCA Associated ... • Drug Associated ... • Levamisole Associated ... against MPO • Complement ... #rheumatology #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immunoglobulins usually associated ... • Low serum C4 complement ... cytoplasmic antibody) associated ... associated with ... diagnosis #types #classification
Treatment algorithm for malignancy-associated hypercalcemia. Hypercalcemia - Renal Failure → Dialysis with low Ca++ bath Aggressive IV hydration
Treatment algorithm ... for malignancy-associated ... #malignancy #associated ... #Treatment #algorithm ... #management #endocrinology
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
Hypertension associated ... Coarctation of aorta, Vasculitis ... • Endocrinologic ... Hyperthyroidism, Hypercalcemia ... Pregnancy-associated
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... Diagnosis: • ANCA-associated ... RNP antibodies, Complement ... Malignancy Associated
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
guide subtype classification ... tubulopathy) - Complement ... formation causing vasculitis ... Types of MGRS-Associated
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