16 results
Fever - Pyrogen Pathophysiology

EXOGENOUS PYROGEN
 • Bacteria: Lipopolysaccharide components, peptidoglycans and muramyl peptide derivatives, Toxins
 •
Fever - Pyrogen ... Lipopolysaccharide components ... stranded RNA • Fungi ... Mannan and glucan components ... production → Fever
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis Algorithm
Neoplasm:
• NHL
• Hodgkin's lymphoma
• Leukemia
• Solid
Causes of Fever ... Differential Diagnosis Algorithm ... Other: • Drug fever ... Infection: • Fungal ... Differential #Diagnosis #Algorithm
ID Approach to Fever and Rash - Diagnostic Algorithm
Central Maculopapular (most common):
Measles, Parvovirus 819 / EBV,
ID Approach to Fever ... Rash - Diagnostic Algorithm ... Viral hemorrhagic fevers ... Disseminated fungal ... Febrile #Diagnosis #Algorithm
Causes of Acute Onset Fever - Differential Diagnosis Algorithm
Viral:
 • Rhinovirus
 • Influenza Virus
 • Parainfluenza
of Acute Onset Fever ... Differential Diagnosis Algorithm ... Infectious - Other: • Fungal ... #Fever #Acute ... Differential #Diagnosis #Algorithm
Fluid-filled Rash - Diagnostic Algorithm.  Pustule: 1) Pustules more commonly suggest an infectious process (bacterial,
Rash - Diagnostic Algorithm ... process (bacterial, fungal ... Pustular #Bullous #Algorithm ... #Differential #Ddxof
“Step by Step” – the new kid on the block – aims to risk stratify this
for each of the components ... of the algorithm ... an infant with fever ... Infant #StepByStep #Algorithm ... Stratification #Fever
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Fever of Unknown ... Refer to your ‘Fever ... Returning Traveler’ algorithm ... the respective fungal ... udaygulati #FUO #Fever
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
Fungal Biomarkers ... Polysaccharide cell wall component ... of many fungi ... post-2010 almost never ... Sara Dong #Fungal
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic Algorithm ... instability - New-onset fever ... Color #Targetoid #Algorithm ... #Differential #Ddxof
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
hypothalamus → fever ... Lipopolysaccharide components ... Double-stranded RNA • Fungi ... Mannan and glucan components